May 16-20, 1999, Moscone Convention Center, SanFrancisco, California USA
With ASBMB Satellite Meetings, May 15-16, 1999:
("The RNA World", and "Cellular Aging and Immortalization").
Keynote Addresses
Thomas A. Steitz, Yale
Univ.
"Structural Principles of
the 50S Ribosomal Subunit Architecture from a 5 Å Resolution Map"
"RNA and the Ribosome"
Harry Noller, Univ. of
California, Santa Cruz
RNA Structure and Folding
- Sat AM
Chair, Jennifer Doudna,
Yale Univ.
"The Hammerhead Ribozyme"
Olke Uhlenbeck, Univ.
of Colorado
"Crystal Structure of Hepatitis
Delta Virus Ribozyme: Clues to Catalysis"
Jennifer Doudna, Yale
Univ.
"Ribosomal RNA Structure
and Function"
Joseph Puglisi, Stanford
Univ.
RNA Therapeutics and Selection
- Sat PM
*Chair, Bruce Sullenger,
Duke Univ.
RNA Editing and Modification
- Sun AM
Chair, Scott A. Strobel,
Yale Univ.
"The Chemical Basis of Group
I Riobozyme Structure and Function"
Scott A. Strobel, Yale
Univ.
Mechanism of Ribosyme - Catalyzed
Phosphoryl Transfer Revealed by Modified Nucleic Acids"
Joseph A. Piccirilli, Univ.
of Chicago
"Modification and Stabilization
in Ribosomal RNA"
James A. McCloskey, Univ.
of Utah
RNA Transport, Localization
and Processing - Sun PM
Chair, Christine Guthrie,
Univ. of California, San Francisco
"Proofreading of RNA during
Export from the Nucleus"
Elsebet Lund, Univ. of
Wisconsin
"Is RNA Processing Linked
to RNA Export?"
Christine Guthrie, Univ.
of California, San Francisco
Keynote Addresses
"A Cellular Basis for Aging
and Cancer"
Judith Campisi, Lawrence
Berkeley Natl. Lab., Berkeley, CA
Mechanisms of Replicative
Senescence - Sat AM
Chair, Calvin Harley, Geron
Corp, Menlo Park, CA
"Telomerase Immortalizes
Normal Human Cell Without Loss of Growth Control or Phenotype"
Calvin Harley, Geron
Corp., Menlo Park, CA
"Activation of Cellular Senescence
by Oncogenic Ras"
Scott Lowe, Cold Spring
Harbor Lab, NY.
"p53 and Genomic Integrity"
*Geoffrey Wahl, Salk
Inst., La Jolla, CA
Cellular Aging - Implications
In Vivo - Sat PM
Chair, Peter Hornsby, Baylor
Col. of Med., Houston, TX
"Cell Transplantation: A
New Technique to Study Cellular Aging"
Peter Hornsby, Baylor
Col. of Med., Houston, TX
"Immune Consequences of T
Cell Replicative Senescence"
Rita Effros, UCLA
"Function Inactivation of
WRN in Mice"
Junko Oshima, Univ. of
Washington, Seattle, WA
Mechanisms of Immortality
- Sun AM
Chair, John Sedivy, Brown
Univ.
"Gene Knockouts and Immortalization
of Human Cells"
John Sedivy, Brown Univ.
"Immortalization of Human
Mammary Epithelial Cells: A Non-viral Perspective"
Paul Yaswen, Lawrence
Berkeley Natl. Lab., Berkeley, CA
"Loss of Genomic Integrity
in Preneoplastic Cells"
Thea Tlsty, Univ. of
California, San Francisco
Cell Immortalization in
Cancer - Sun PM
Chair, Catherine Reznikoff,
Univ. of Wisconsin, Madison
"Bypassing Tumor Suppressor
Checkpoints in Cell Immortalization"
Catherine Reznikoff, Univ.
of Wisconsin, Madison
"Molecular Mechanisms for
Normal Mammary Epithelial Cell Immortalization"
Vimla Band, New England
Med. Ctr., Boston, MA
"Tumor Suppressors, Telomerase
and Tumors in the Mouse"
Ronald DePinho, Dana-Farber
Inst., Boston MA
Cell Cycle
Chair, John Newport, Univ.
of California, San Diego
"Regulation of Yeast Chromosome
Replication"
Bonita J. Brewer, Univ.
of Washington
"Exit from Mitosis"
Andrew Murray, Univ.
of California, San Francisco
"Regulation of the Embryonic
Cell Cycle"
John Newport, Univ. of
California, San Diego
"DNA Damage Checkpoint Control"
*Paul Russell, Scripps
Res. Inst.
Apoptosis
Chair, Vishva Dixit, Genentech, Inc.
"Caspases and their Roles
in Apoptosis"
Nancy Thornberry, Merck
Res. Labs., Rahway, NJ
"The Role of Cell Death in
Normal Physiology and in Disease"
Andreas Strasser, Walter
and Eliza Inst. of Med. Res.,Australia
"Apoptosis Regulation by
Death and Decoy Receptors"
Avi Ashkenazi, Genentech,
Inc.
"Genetic Control of Programmed
Cell Death in C. elegans"
Michael O. Hengartner, Cold
Spring Harbor Labs.
Cell Motility
Chair, James Spudich, Stanford
Univ.
"Kinesin-Driven Microtubule
Motility"
Ron Vale, Univ. of California,
San Francisco
"DNA Polymerase Movement
along DNA"
Lorena Beese, Duke Univ.
Med. Ctr.
"Regulation of Myosin Assembly
and Function"
James Spudich, Stanford
Univ.
"KIF2 Protein Function in
Developing Neurons"
Alfredo Caceres, Natl.
Res. Council, Argentina
Protein and Membrane Traffic
in the Eukaryotic Cell
Chair, Randy Schekman, HHMI,
Univ. of California, Berkeley
"Regulation of Nucleocytoplasmic
Transport"
Erin O'Shea, Univ. of
California, San Francisco
"Lipid Kinase and GTPase
Regulators of Lysosomal Protein Traffic"
Scott Emr, Univ. of California,
San Diego
"Molecular Analysis of Receptor
Trafficking"
Suzanne Pfeffer, Stanford
Univ. Sch. of Med.
"Mechanism of Protein Sorting
and Vesicle Budding"
Randy Schekman, HHMI,
Univ. of California, Berkeley
Immunology
Chair, Richard A. Flavell,
HHMI, Yale Univ. Sch. of Med.
"The Molecular Basis for
T-Cell Differentiation"
Richard A. Flavell, HHMI,
Yale Univ. Sch. of Med.
"Regulation of the Assembly
of MHC-Peptide Complexes"
Peter Cresswell, HHMI, Yale
Univ. Sch. of Med.
"Engineering Autoimmunity"
Diane Mathis, IGBMC,
France
"Nf-kB's Many Facets"
David Baltimore, California
Inst. of Tech.
Proteases in Diseases
Chair, Nancy Thornberry,
Merck Res. Labs, Rahway, NJ
"Extracellular Matrix Proteolysis:
New Roles and Novel Targets in Human Disease"
Bill Stetler-Stevenson,
National Cancer Inst., NIH
"Proteases as Triggers of
Inflammation"
Roy Black, Immunex
"Viral Proteases: The Achilles
Heel of Viral Infections"
Charles Craik, Univ.
of California, San Francisco
"Molecular Role of Caspases
in Apoptotic Cell Suicide and Human Disease Pathogenesis"
Don Nicholson, Merck
Frosst Centre for Therapeutic Research
"Biochemical Dissection of
the Eukaryotic Transcriptional Machinery"
Robert Tjian, Univ. of
California, Berkeley
"The Interface of Signal
Transduction and Chromatin Regulation"
Gerald Crabtree, Stanford
Univ.
"Transcriptional Control
of Cardiovascular Development and Disease"
Eric Olson, Univ. of
Texas Southwestern Med. Ctr.
"G Proteins and Regulation
of Adenylyl Cyclase"
Alfred Gilman, Univ.
of Texas Southwestern Med. Ctr.
Human Genome
Chair, David Botstein, Stanford
Univ. Sch. of Med.
"Getting at Gene Function
Using Microarray Hybridization"
Patrick O. Brown, Stanford
Univ.
"The Genes that Carry Out
the Core Biology in Yeast and Worm Are the Same"
David Botstein, Stanford
Univ. Sch. of Med.
"Genomes, Mouse Genetics
and Skeletal Development"
David Kingsley, Stanford
Univ.
"Placing Genes on Pathways
using Drosophila Genetics and Genomes"
Gerald Rubin, Univ. of
California, Berkeley
Gene Regulation, Session
I
Chair, Steven L. McKnight,
Univ. of Texas Southwestern Med. Ctr.
"Molecular Genetics of Circadian
Rythms in Mammals"
Joseph S. Takahashi, HHMI,
Northwestern Univ.
"Molecular Genetics of Circadian
Rhythms in Drosophila"
Michael Rosbash, HHMI,
Brandeis Univ.
"Circadian Gene Expression
in Animal and Cells"
Ueli Schibler, Universite
de Geneve, Switzerland
"New PAS Domain Proteins
- New Biological Surprises"
Steven McKnight, Univ.
of Texas Southwestern Med. Ctr.
Gene Regulation: Structures,
Strategies, and Signals
Chair, Robert N. Eisenman,
Fred Hutchinson Cancer Res. Ctr.
"Eukaryotic Gene Expression:
A Structuralist's View"
Stephen K. Burley, HHMI,
Rockefeller Univ.
"TGFb Signaling Specificity
in the Early Vertebrate Embryo"
Malcolm Whitman, Harvard
Med. Sch.
"Dissecting Transcriptional
Regulatory Circuitry in Yeast"
Richard Young, Whitehead
Inst., MIT
"A Transcription Factor Network
Regulating Cell Proliferation and Differentiation"
Robert N. Eisenman, Fred
Hutchinson Cancer Res. Ctr.
Signal Transduction, Session
I
Chair, Jack E. Dixon, Univ.
of Michigan
"Function of PTB Domain Proteins"
Benjamin Margolis, HHMI,
Univ. of Michigan Med. Sch.
"Phosphoryl Transfer: Its
Importance in Signal Transduction"
Jack E. Dixon, Univ.
of Michigan
"Signaling by Protein-Tyrosine
Kinases and Phosphatases"
Tony Hunter, Salk Inst.
"Spatial Compartmentalization
in Insulin Action"
Alan R. Saltiel, Parke-Davis
Pharmaceutical Res., Inc.
Oncogenes/Antioncogenes
Chair, Carol Prives, Columbia
Univ.
"New Insights into p53 Regulation"
James Sherley, MIT
"Genetic Analysis of Cancer
Development using Mutant Mice"
Alan Bernstein, Samuel
Lunenfeld Res. Inst., Toronto
"Function of the NF2 Tumor
Suppressor, Merlin, in vivo and in vitro"
Andrea I. McClatchy, Massachusetts
Gen. Hosp.
"Regulation of the p53 Anti-Oncogene/Oncogene"
Carol Prives, Columbia
Univ.
Signal Transduction, Session
II
Chair, Joseph Schlessinger,
NYU Sch. of Med.
"Cellular Signaling by Tyrosine
Phosphorylation"
Joseph Schlessinger, New
York Univ. Med. Ctr.
"Signaling by TGFb Receptors"
Joan Massague, Mem. Sloan-Kettering
Cancer Inst.
"The Role of PI-3 Kinase
in Cell Signaling"
Lewis Cantley, Harvard
Institutes of Medicine
"Ras Signaling and Growth
Control"
Dafna Bar-Sagi, SUNY
at Stony Brook
"Generating New Molecular
Function: A Lesson From Nature"
Peter Schultz, Univ.
of California, Berkeley
Combinatorial Chemistry
Chair, Jonathan Ellman,
Univ. of California, Berkeley
"Combinatorial Technologies
for the Generation of Primary Screening Libraries"
Mark Gallop, Affymax
Res. Inst.
"Combinatorial Approaches
to Somatostatin Receptor Family Ligands"
Kevin Chapman, Merck
Res. Lab.
"Ligand Discovery Using Small
Molecule Libraries"
Jonathan Ellman, Univ.
of California, Berkeley
Combinatorial Biology
Chair, Gerald Joyce, Scripps
Res. Inst.
"RNA-Directed Combinatorial
Chemistry"
Bruce Eaton, NeXstar
Pharm., Inc., Boulder, CO
"Ligand-Specific Molecular
Switches Composed of RNA"
Ronald Breaker, Yale
Univ.
"Continuous in vitro Evolution
of RNA Enzymes"
Gerald Joyce, Scripps
Res. Inst.
"In vitro Evolution of Polypeptides
Based on RNA-Protein Fusions"
Jack Szostak, Harvard
Med. Sch., Massachusetts Gen. Hosp.
Enzyme Structure/Function
Chairs, Stephen J. Benkovic,
Pennsylvania State Univ.
Daniel V. Santi, Univ.
of California, San Francisco
*Dagmar Ringe, Brandeis
Univ.
*Stephen Withers, Univ.
of British Columbia
Discovery of Ligands for
Biological Receptors
Chair, Gregory L. Verdine,
Harvard Univ.
"Regulation of Gene Expression
by Synthetic DNA Binding Ligands"
Peter B. Dervan, California
Inst. of Technology
"Peptide Morphing"
Gregory L. Verdine, Harvard
Univ.
"Binding at Protein Interfaces"
James A. Wells, Sunesis
Pharm. Inc.
Enzymes - General
Chair, Jack Kirsch, Univ
of California, Berkeley and Judith Klinman, Univ. of California,
Berkeley
"Carbamoyl Phosphate Synthetase:
Three Active Sites Connected by Two Molecular Tunnels"
Frank Raushel, Texas
A&M Univ.
"Mechanism of Ribonuclease
P: Synergy between the Protein and RNA Subunits"
Carol Fierke, Duke Univ.
Med. Ctr.
"Phosphoryl Transfer: Transition
States, Catalysis and Evolution of Enzyme Diversity"
Daniel Herschlag, Stanford
Univ.
"New Developments in PLP-dependent
Enzyme Mechanisms"
Jack Kirsch, Univ. of
California, Berkeley
Protein Design/Folding
Chairs, William F. DeGrado,
Univ. of Pennsylvania and Lynne Regan, Yale Univ.
"Assisted Protein Biogenesis
in the Bacterial Cytoplasm"
Alejandro M. Visle, Univ.
of Rosario, Argentina
"De Novo Protein Design"
William F. DeGrado, Univ.
of Pennsylvania
"Designing Proteins with
Novel Structures and Activities"
Lynne Regan Yale Univ.
"Automated Design of Functional
Metal-Binding Sites in Proteins"
Homme Hellinga, Duke
Univ.
Computational Biology
Chair, Peter Kollman, Univ.
of California, San Francisco
"Towards the Prediction of
Protein Structure and Function on a Genomic Scale"
Jeffrey Skolnick, Scripps
Res. Inst.
"Probing Protein Stability
through Computational Protein Design"
Stephen L. Mayo, HHMI,
California Inst. of Tech.
"MD Simulations of Anomalous
DNA Structures"
Modesto Orozco, Univ.
of Barcelona, Spain
"Protein and Nucleic Acid
Structures and Free Energies: What Can Simulations Say?"
Peter Kollman, Univ.
of California, San Francisco
Mitochondrial Mechanisms
in Energy Generation, Metabolic Control, Disease and Death
Chair, Shelagh Ferguson-Miller,
Michigan State Univ.
"Cytochrome Oxidase: Energy
Generator of Aerobic Life"
Shelagh Ferguson-Miller,
Michigan State Univ.
"Subunit Structure and Organization
in the Protonmotive Rotary Motor of F0F1ATP Synthase"
Robert H. Fillingame, Univ.
of Wisconsin, Madison
"Transport Mechanisms of
Mammalian Mitochondrial Uncoupling Proteins"
Keith D. Garlid, Oregon
Graduate Inst. of Science & Tech.
"Excess Superoxide Production
and Variable bcl-2 Expression: Determinants of Cell Viability and Clinical
Severity in Human Mitochondrial Complex I Deficiency"
Brian H. Robinson, Hosp.
For Sick Children, Toronto, Canada
New Structures and Methods
Chair, Robert M. Stroud,
Univ. of California, San Francisco
"What the Structure of gp120
Complexes Instruct about Interaction with CD4 and the Chemokine Receptors,
and the Antigenic Response to HIV"
Wayne Hendrickson, Columbia
Univ.
"How SNAP receptor Proteins
lead to targeted fusion of secretory vesicles in neuronal linkages, and
in eukaryotic cells"
Axel Brunger, Yale Univ.
"Understanding Transmembrane
Potassium Channel Selectivity, and Conductivity"
Rod MacKinnon, Columbia
Univ.
"How is Signal Transduction
Encoded in the EPO and Cytokine Receptor Family?"
Robert Stroud, Univ.
of California, San Francisco
"Brassinosteroids the Regulation
of Plant Stature"
Joanne Chory, The Salk
Inst.
"Molecular Genetics of Biological
Clocks in Plants"
Steve A. Kay, Scripps
Res. Inst.
"Genes Involved in Lignification
and Digestibility in Cereals"
Pedro Puigdomenech Rossel,
Dept. Genética Molecular, C.I.D., Spain
"Structural and Cellular
Basis of Pathogen Derived Resistance to Virus Infection"
Roger N. Beachy, Scripps
Res. Inst.
Emerging Technologies
Chair, Steve Fodor, Affymetrix
"Generating Diversity: Where
Next?"
Peter G. Schultz, Univ.
of California, Berkeley
"Genomics and DNA Chips"
David Lockhart, Affymetrix
"Quantitative Mapping of
Intracellular Biochemical Pathways by Protein Fragment Complementation
Strategies"
Stephen Michnick, Universite
de Montreal
"Molecular Breeding of Proteins,
Pathways and Genomes by DNA Suffling"
Pim Stemmer, Maxygen,
Santa Clara, CA
"Mass Spectrometry and the
Proteome: Emerging Methods to Help Define Protein Function"
John Yates, Univ. of
Washington
New Protein Therapeutics
Chair, Neil Stahl, Regeneron,
Tarrytown, NY
"Genomics to Therapeutic
Antibodies"
Ron Lindsay, Millenium
Biotherapeutics
"Osteoprotegrin: Positive
and Negative Regulation of Osteoclastogenesis and Bone Density"
William Boyle, Amgen,
Inc.
"Cytokine Traps: Heterodimeric
High Affinity Cytokine Antagonists"
Neil Stahl, Regeneron,
Tarrytown, NY
Gene Therapy
Chair, Gary Nabel, HHMI,
Univ. of Michigan Med. Ctr.
"Gene Therapy for Hemophillia"
Inder M. Verma, The Salk
Inst.
"RNA Repair as a Novel Approach
to Genetic Therapy"
Bruce A. Sullenger, Duke
Univ.
"Long-term Gene Expression
in Dystrophic Muscle from Gutted Adenoviral Vectors"
Jeffrey S. Chamberlain,
Univ. of Michigan
"Gene Therapy for AIDS and
Emerging Viruses"
Gary J. Nabel, HHMI,
Univ. of Michigan Med. Ctr.
ASBMB-Merck Award
"Nature of the Apomyoglobin
Folding Pathway"
Robert L. Baldwin, Stanford
Univ.
William C. Rose Award
"Metabolic Control of Gene
Transcription"
Richard W. Hanson, Case
Western Reserve Univ.
Schering-Plough Scientific
Achievement Award
"The Mitogen Activated Protein
Kinase Pathway: From the Cell Surface to the Nucleus"
Kun-Liang Guan, Univ.
of Michigan
Fritz Lipmann Award
"NMR as a Tool in Drug Research"
Steve Fesik, Abbott Labs.
IUBMB/PABMB Lecture
PABMB Award Lecture
FEBS/PABMB Lecture
The Roche Diagnostic Award for Biomolecular and Cellular Research
"Modular Polyketide Synthases
Chaitan Khosla, Stanford
Univ.
"Experimental and Theoretical
Tools to Analyze Metabolic Networks"
James T. Bailey, ETH,
Zurich
"Genomic Tools to Analyze
Metabolism"
Camilla Kao, HHMI, Stanford
Univ.
"Bacterial and Fungal Aromatic
Natural Product Biosynthesis"
C. Richard Hutchinson, Univ.
of Wisconsin
The Repligen Award for
Chemistry in Biological Processes Enzymes, Cofactors and Antibiotics
Chair, Christopher T. Walsh,
Harvard Med. Sch.
"Mechanistic Studies in Thiamin
Biosynthesis and Degradation"
Tadhg Begley, Cornell
Univ.
"Molecular Origins of Antibiotic
Resistance"
Gerry Wright, McMaster
University, Ontario
"Learning Nature's Strategies
of Making Deoxysugars: Pathways, Mechanisms, and Combinatorial Biosynthetic
Applications"
Hung-Wen Liu, Univ. of
Minnesota
"Molecular Catalysts in the
Biosynthesis of Nonribosomal Peptide Antibiotics"
Christopher T. Walsh, Harvard
Med. Sch.
The Pfizer Award in Enzyme
Chemistry "Structure, Mechanism and Evolution of Metalloenzymes"
Chair, David Christianson,
Univ. of Pennsylvania
"Catalytic Mechanisms of
Zinc Metalloenzymes"
Carol Fierke, Duke Univ.
Med. Ctr.
"Envisioning NO Synthesis
from Arginine: Nitric Oxide Synthase Structures with Bound Substrate, Products
and Inhibitors"
John Tainer, Scripps
Res. Inst.
"Structural Biology of Molybdenum
and Tungsten Containing Enzymes"
Douglas C. Rees, California
Inst. of Technology
"Structure, Mechanism and
Physiology of Manganese Metalloenzymes"
David Christianson, Univ.
of Pennsylvania
Insight into Mechanisms
Based on Structure
Chair, Marian T. Stankovich,
Univ. of Minnesota
Structure/Function of Medium
Chain Acyl-CoA Dehydrogenase: The Importance of Substrate Polarization
Marian T. Stankovich,
Univ. of Minnesota
Structure/Function Studies
of Escherichia coli Adenylosuccinate Synthetase
Herbert J. Fromm, Iowa
State Univ.
Structure and Mechainsm of
3-Oxo-D 5-Steroid Isomerase
Ralph Pollack, Univ.
of Maryland, Baltimore County
Structure and Mechanism of
Protein Farnesyltransferase
Lorena S. Beese, Duke
Univ. Med. Ctr.
Allosteric Regulation
of Enzymes
Chair: Gregory D. Reinhart,
Texas A&M Univ.
Allosteric Control Mechanisms
of Glycerol Kinase from Escherichia coli in vitro and in vivo
Donald W. Pettigrew, C.
Kay Holtman and Aaron C. Pawlyk, Texas A&M Univ.
Energetics and the Allosteric
Mechanism of Phosphofructokinase from Bacillus Stearothermophilus
Gregory D. Reinhart, Texas
A&M Univ.
How Conformational Change
Couples Chemistry in the ATP Sulfurylase-GTPase System
Thomas Leyh, Albert Einstein
Col. Med.
The Mechanism of Allosteric
Activation of Yeast Pyruvate Kinase
Thomas Nowak, Univ. of
Notre Dame
"Amphipathic Exchangeable
Apolipoproteins: Molecular Aspects of Lipid Interaction and Receptor Binding"
Robert O. Ryan, Univ.
of Alberta
"Apolipoprotein E: What its
Structure is Revealing"
Karl Weisgraber, Univ.
of California, San Francisco
"The Role of Conformational
Dynamics and Stability in apo A-I Lipid Binding"
Christie Brouillette, Univ.
of Alabama at Birmingham
"Protein Factors Involved
in VLDL Assembly and Secretion"
Zemin Yao, Univ. of Ottawa
Heart Inst.
"Molecular Determinants of
Lecithin: Cholesteral Acyltransferase Activity and Fatty Acyl Substrate
Specificity"
John Parks, Bowman Gray
Sch. of Med.
"The Role Lipoprotein Chemical
Modifications in the Reverse Cholesterol Transport System"
Eder C. R. Quintão,
Universidade Sao Paulo, Brazil
Membrane Transport Proteins
Chairs, Carol E. Cass, Univ.
of Alberta and Reinhart Reithmeier, Univ. of Toronto
"The Transporters of Microorganisms:
From Databases to Membrane Proteins"
Karen Ketchum, Inst.
For Genomic Res., Rockville, MD
"Structure and Mechanism
of the Human Multidrug Resistance P-glycoprotein"
David M. Clarke, Univ.
of Toronto
"Misfolding and Degradation
of Proteins in the Endoplasmic Reticulum"
Ron R. Kopito, Stanford
Univ.
"The Aquaporins: Components
of Cellular Plumbing Systems"
Peter Agre, Johns Hopkins
Univ.
"Nucleoside Transporters
and Therapeutics"
Carol E. Cass, Univ.
of Alberta
"Modulation of Chloroplast
Enzymes by Reduced Thioredoxin"
Ricardo A. Wolosiuk, Univ.
of Buenos Aires, Argentina
"Biosynthesis of Cell Wall
Polysaccharides in the Golgi apparatus from Plant Cells"
Ariel Orellana, Univ.
of Chile
"Translocation of Mammalian
Glycogen Synthases"
Joan Guinovart, Univ.
of Barcelona, Spain
"The Role of Glucokinase
Translocation in the Control of Hepatic Glucose Metabolism"
Loranne Agius, Univ.
of Newcastle upon Tyne, United Kingdom
Glycan Structure and Synthesis
in Lower Eukaryotes
Chairs, Armando Parodi,
Inst. De Invest. Bioquimicas Fundacion Campomar, Argentina and Salvatore
Turco, Univ. of Kentucky Med. Ctr.
"Quality Control of Glycoprotein
Folding in Yeasts"
Armando Parodi, Inst.
De Invest. Bioquimicas Fundacion Campomar, Argentina
"Genetics and Biochemistry
of Lipopolysaccharide Synthesis in Leishmania donovani"
Salvatore Turco, Univ.
of Kentucky Med. Ctr.
"Structure and Biosynthesis
of Mucins in Trypanosoma cruzi"
Lucia Mendonca-Previato,
Univ. Federal de Rio de Janeiro, Brazil
"Genetics and Structure of
Glycosylphosphatidylinositol Anchors in Saccharomyces cerevisiae"
Peter Orlean, Univ. of
Illinois, Urbana-Champaign
Calcium Signaling and
Transport Systems
Chairs, Cecilia Hidalgo,
ICBM,Univ. of Chile, Santiago, Chile and Leopoldo de Meis, CID,
Univ. of Fundao, Rio de Janeiro, Brazil
"Heat Generation and Body
Temperature Control by the Ca2+ Transport ATPase of Skeletal Muscle"
Leopoldo de Meis, CID,
Univ. of Fundao, Rio de Janeiro, Brazil
"Inherited Muscle Diseases
Arising from Defects in Calcium Regulatory Proteins"
David H. MacLennan, Univ.
of Toronto
"Calcium Imaging with Genetically
Encoded Fluorescent Indicators"
Roger Tsien, HHMI, Univ.
of California, San Diego
"Cytoplasmic and Luminal
Regulation of Sarcoplasmic reticulum Calcium Release Channels"
Cecilia Hidalgo, ICBM,Univ.
of Chile, Santiago, Chile
Neurochemistry
Chair, Fernando G. de Mello, Universidade Federal de Rio de Janeiro, Brazil
"ADDLs and Fyn: A New Basis
for Pathogenesis in Alzheimer's Disease"
William L. Klein, Northwestern
Univ.
"Molecular Chaperones Modulate
Amiloid Beta Peptide Assembly and Neurotoxicity"
Nibaldo C. Inestrosa, Catholic
Univ. of Chile
"Lipid Modulation of Nicotinic
Acetylcholine Receptor in Health and Pathological Conditions"
Francisco J. Barrantes,
Univ. Nacional del Sur, Bahia Blanca, Argentina
"Changes in the Cholinergic
Phenotype Induced by Excitatory Amino Acid Agonists"
Fernando G. de Mello, Universidade
Federal de Rio de Janeiro, Brazil
"Role of Shared Resources
in Multilaboratory Research"
Ronald L. Niece, Univ.
of California, Irvine
"Sequencing the Genome of
Xylella fastidicosa"
Fernando C. Reinach, Univ.
of Sao Paulo, Brazil
"Macromolecular Crystallography
in South America and the National Syncrotron Source for X-ray Diffraction"
Raghuvir K. Arni, IBILCE/UNESP,
Brazil
"Protein Folding Intermediates
as Studied by Hydrostatic Pressure"
Jerson L. Silva, Federal
Univ. of Rio de Janeiro, Brazil
"Rational Design and Biodiversity
in the Search for New Antichagasic Drugs"
Glaucius Oliva, Univ.
of Sao Paulo-Sao Carlos, Brazil
"Characterization, Possible
Origins and Biological Significance of Deterministic Behavior in Protein
Folding and Subunit Interactions."
Sergio. T. Ferreira, Federal
Univ. of Rio de Janeiro, Brazil
"Experiments from the Desk
Instead of the Bench: Why Should a Scientist Become a Dean?"
Thomas D. Landefeld, California
State Univ. - Dominguez Hills
"Tenure: Obstacle or Opportunity"
Linda Washington, Argonne
Natl. Lab.
"From Postdoc to Assistant
Professor: Jumping the Hurdles Without Breaking Your Legs"
Frank Talamantes, Univ.
of California, Santa Cruz
"Survival 101: What They
Don't Tell You in/about Graduate School"
Theresa M. Duello, Univ.
of Wisconsin Sch. of Med.
The Diversity of Career
Options in the Bio/Pharmaceutical and Biotechnology Industries
Chair, A. Stephen Dahms,
San Diego State Univ.
"Changing Employment Patterns
for PhD's in the Life Sciences"
Paula Stephan, School
of Policy Studies, Georgia Tech.
"Career Opportunities for
the Graduate Scientist"
Mark D. Dibner, Inst.
for Biotechnology Information, Res. Triangle Park, NC
"Alternate Careers in Science:
Leaving the Ivory Tower?"
Cynthia Robbins-Roth, BioVenture
Consultants, San Francisco
"The Career View from Inside
a Biotechnology Company"
Judith Heyboer, Genentech,
Inc.
"Biotechnology Workforce
Needs"
A. Stephen Dahms, Ctr.
Pharmaceutical & Biodevice Development, San Diego State Univ.
The Boyer Report: Implications
and Can it Be Implemented?
Chair, Hal White, Univ.
of Delaware and Carl Rhodes, Stanford Univ.
"Stanford's Science, Mathematics
and Engineering Core: Science Literacy for Tomorrow's Leaders"
Robert D. Simoni, Stanford
Univ.
"Studio Biochemistry at Rensselaer"
Joe Warden and Joyce Diwan,
Rensselaer Polytech Inst.
"Transforming Undergraduate
Education: Problem-Based Learning at the Univ. of Delaware"
Hal White, Univ. of Delaware
"Cooperative Learning in
Biochemistry Education"
Alan Attie, Univ. of
Wisconsin
The New ACS Biochemistry
Requirement: Implications for Chemists and Biochemists
Chair, Adele J. Wolfson,
Wellesley College
"ACS-CPT New Biochemistry
Requirement"
Elizabeth C. Theil, Children's
Hosp. Oakland Res. Inst.
"Experience of the University
of Delaware in Requiring a Biochemistry Course for the Chemistry Major"
Roberta F. Colman, Univ.
of Delaware
"Introducing Biochemical
Material into the Organic Sequence"
William Fuchsman, Oberlin
College
"Introducing Biochemistry
into Introductory Chemistry"
Adele J. Wolfson, Wellesley
College
Biochemistry Teaching
Laboratories: New Ideas
Chair, Ellis Bell, Gustavus
Adolphus College
"Lab Manuals: Homemade or
Store-Bought"
Rodney Boyer, Hope College
"A Place for Molecular Genetics
and Recombinant DNA in a Biochemistry Course"
Victor Romanowski, Univ.
Nacional de La Plata, Univ. Nacional de Quilmes, Argentina
"Creating the Research Mind
Set in a Teaching Laboratory"
Ellis Bell, Gustavus
Adolphus College
"Designing Computer-based
Learning Tools: Merging Pedagogy and Technology"
Gabriele Weinhausen, Univ.
of California, San Deigo
"Modules and Integration:
Biochemistry Across the Undergraduate Curriculum"
Christopher E. Rohlman,
Pomona College
Panel Discussion: Program
Assessment
Chairs, John A. Boyle, Mississippi
State Univ. and Terry S. Woodin, Natl. Science Found.
Panelists:
Shelagh Ferguson-Miller,
Michigan State Univ.
Judith G. Voet, Swathmore
College
Marion H. O'Leary, California
State Univ., Sacramento
Elizabeth C. Theil, Children's
Hosp. Oakland Res. Inst.
Biochemical Education Across the Americas
Chair, Ed Wood, Univ. of Leeds, UK and Leopoldo de Meis, Federal Univ. of Rio de Janeiro, Brazil
"Biochemical Education in
Chile"
Manuel Krauskopf, Chile
"Biochemistry and Molecular
Biology: A Southern Look"
Hector Torres, Argentina
"Supporting Scientific Education
and Investigation in the Americas"
Eva Harris, SFO
"Biochemistry Courses in
Central America: Limitations and Opportunities"
Olga Torres, Guatemala