Published in Genome Research, vol. 13, no. 6b, pp. 1265- (June2, 2003).
http://www.genome.org/content/vol13/issue6b/index.shtml

Report of "RIKEN Mouse Genome Encyclopedia" project: the whole system from mouse house to database.

PREFACE:

Yoshihide Hayashizaki
     Special FANTOM2 Issue
     Genome Res. 2003 13: 1265. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1265

COMMENTARY:

Yasushi Okazaki and David A. Hume
     A Guide to the Mammalian Genome
     Genome Res. 2003 13: 1267-1272. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1267

ARTICLES:

Piero Carninci, Kazunori Waki, Toshiyuki Shiraki, Hideaki Konno, Kazuhiro Shibata, Masayoshi Itoh, Katsunori
Aizawa, Takahiro Arakawa, Yoshiyuki Ishii, Daisuke Sasaki, Hidemasa Bono, Shinji Kondo, Yuichi Sugahara, Rintaro Saito, Naoki Osato, Shiro Fukuda, Kenjiro Sato, Akira Watahiki, Tomoko Hirozane-Kishikawa, Mari Nakamura, Yuko Shibata, Ayako Yasunishi, Noriko Kikuchi, Atsushi Yoshiki, Moriaki Kusakabe, Stefano Gustincich, Kirk Beisel, William Pavan, Vassilis Aidinis, Akira Nakagawara, William A. Held, Hiroo Iwata, Tomohiro Kono, Hiromitsu Nakauchi, Paul Lyons, Christine Wells, David A. Hume, Michela Fagiolini, Takao K. Hensch, Michelle Brinkmeier, Sally Camper, Junji Hirota, Peter Mombaerts, Masami Muramatsu, Yasushi Okazaki, Jun Kawai, and Yoshihide Hayashizaki
     Targeting a Complex Transcriptome: The Construction of the Mouse Full-Length cDNA Encyclopedia
     Genome Res. 2003 13: 1273-1289. [Abstract] [Full Text] [Supplemental Research Data]
      http://www.genome.org/cgi/content/abstract/13/6b/1273

Mihaela Zavolan, Shinji Kondo, Christian Schönbach, Jun Adachi, David A. Hume, RIKEN GER Group, GSL
Members, Yoshihide Hayashizaki, and Terry Gaasterland
     Impact of Alternative Initiation, Splicing, and Termination on the Diversity of the mRNA Transcripts
     Encoded by the Mouse Transcriptome
     Genome Res. 2003 13: 1290-1300. [Abstract] [Full Text] [Supplemental Research Data]
      http://www.genome.org/cgi/content/abstract/13/6b/1290

Koji Numata, Akio Kanai, Rintaro Saito, Shinji Kondo, Jun Adachi, Laurens G. Wilming, David A. Hume, RIKEN GER Group, GSL Members, Yoshihide Hayashizaki, and Masaru Tomita
     Identification of Putative Noncoding RNAs Among the RIKEN Mouse Full-Length cDNA Collection
     Genome Res. 2003 13: 1301-1306. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1301

Vladimir Brusic, Rekha S. Pillai, Diego G. Silva, Nikolai Petrovsky, RIKEN GER Group, GSL Members, and Christian Schönbach
     Cytokine-Related Genes Identified From the RIKEN Full-Length Mouse cDNA Data Set
     Genome Res. 2003 13: 1307-1317. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1307

LETTERS:

Hidemasa Bono, Ken Yagi, Takeya Kasukawa, Itoshi Nikaido, Naoko Tominaga, Rika Miki, Yosuke Mizuno,
Yasuhiro Tomaru, Hitoshi Goto, Hiroyuki Nitanda, Daisuke Shimizu, Hirochika Makino, Tomoyuki Morita, Junshin Fujiyama, Takehito Sakai, Takashi Shimoji, David A. Hume, Yoshihide Hayashizaki, and Yasushi Okazaki
     Systematic Expression Profiling of the Mouse Transcriptome Using RIKEN cDNA Microarrays
     Genome Res. 2003 13: 1318-1323. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1318

Hidenori Kiyosawa, Itaru Yamanaka, Naoki Osato, Shinji Kondo, and Yoshihide Hayashizaki
     Antisense Transcripts With FANTOM2 Clone Set and Their Implications for Gene Regulation
     Genome Res. 2003 13: 1324-1334. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1324

Alexander Kanapin, Serge Batalov, Melissa J. Davis, Julian Gough, Sean Grimmond, Hideya Kawaji, Michele
Magrane, Hideo Matsuda, Christian Schönbach, Rohan D. Teasdale, and Zheng Yuan
     Mouse Proteome Analysis
     Genome Res. 2003 13: 1335-1344. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1335

Hidemasa Bono, Itoshi Nikaido, Takeya Kasukawa, Yoshihide Hayashizaki, and Yasushi Okazaki
     Comprehensive Analysis of the Mouse Metabolome Based on the Transcriptome
     Genome Res. 2003 13: 1345-1349. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1345

Sean M. Grimmond, Kevin C. Miranda, Zheng Yuan, Melissa J. Davis, David A. Hume, Ken Yagi, Naoko Tominaga, Hidemasa Bono, Yoshihide Hayashizaki, Yasushi Okazaki, and Rohan D. Teasdale
     The Mouse Secretome: Functional Classification of the Proteins Secreted Into the Extracellular
     Environment
     Genome Res. 2003 13: 1350-1359. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1350

Christine A. Wells, Timothy Ravasi, Razvan Sultana, Ken Yagi, Piero Carninci, Hidemasa Bono, Geoffrey Faulkner, Yasushi Okazaki, John Quackenbush, David A. Hume, and Paul A. Lyons
     Continued Discovery of Transcriptional Units Expressed in Cells of the Mouse Mononuclear Phagocyte
     Lineage
     Genome Res. 2003 13: 1360-1365. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1360

Alistair R.R. Forrest, Darrin Taylor, and Sean Grimmond
     Exploration of the Cell-Cycle Genes Found Within the RIKEN FANTOM2 Data Set
     Genome Res. 2003 13: 1366-1375. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1366

John C. Reed, Kutbuddin Doctor, Ana Rojas, Juan M. Zapata, Christian Stehlik, Loredana Fiorentino, Jason Damiano, Wilfried Roth, Shu-ichi Matsuzawa, Ruchi Newman, Shinichi Takayama, Hiroyuki Marusawa, Famming Xu, Guy Salvesen, and Adam Godzik
     Comparative Analysis of Apoptosis and Inflammation Genes of Mice and Humans
     Genome Res. 2003 13: 1376-1388. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1376

Colin A.M. Semple, RIKEN GER Group, and GSL Members
     The Comparative Proteomics of Ubiquitination in Mouse
     Genome Res. 2003 13: 1389-1394. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1389

Stefano Gustincich, Serge Batalov, Kirk W. Beisel, Hidemasa Bono, Piero Carninci, Colin F. Fletcher, Sean Grimmond, Nobutaka Hirokawa, Erich D. Jarvis, Tim Jegla, Yuka Kawasawa, Julianna LeMieux, Harukata Miki, Elio Raviola, Rohan D. Teasdale, Naoko Tominaga, Ken Yagi, Andreas Zimmer, RIKEN GER Group, GSL Members, Yoshihide Hayashizaki, and Yasushi Okazaki
     Analysis of the Mouse Transcriptome for Genes Involved in the Function of the Nervous System
     Genome Res. 2003 13: 1395-1401. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1395

Itoshi Nikaido, Chika Saito, Yosuke Mizuno, Makiko Meguro, Hidemasa Bono, Moritoshi Kadomura, Tomohiro
Kono, Gerard A. Morris, Paul A. Lyons, Mitsuo Oshimura, RIKEN GER Group, GSL Members, Yoshihide Hayashizaki, and Yasushi Okazaki
     Discovery of Imprinted Transcripts in the Mouse Transcriptome Using Large-Scale Expression Profiling
     Genome Res. 2003 13: 1402-1409. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1402

Rebecca Holmes, Christine Williamson, Jo Peters, Paul Denny, RIKEN GER Group, GSL Members, and Christine Wells
     A Comprehensive Transcript Map of the Mouse Gnas Imprinted Complex
     Genome Res. 2003 13: 1410-1415. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1410

Khairina Tajul-Arifin, Rohan Teasdale, Timothy Ravasi, David A. Hume, RIKEN GER Group, GSL Members, and John S. Mattick
     Identification and Analysis of Chromodomain-Containing Proteins Encoded in the Mouse Transcriptome
     Genome Res. 2003 13: 1416-1429. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1416

Timothy Ravasi, Thomas Huber, Mihaela Zavolan, Alistair Forrest, Terry Gaasterland, Sean Grimmond, RIKEN GER Group, GSL Members, and David A. Hume
     Systematic Characterization of the Zinc-Finger-Containing Proteins in the Mouse Transcriptome
     Genome Res. 2003 13: 1430-1442. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1430

Alistair R.R. Forrest, Timothy Ravasi, Darrin Taylor, Thomas Huber, David A. Hume, RIKEN GER Group, GSL Members, and Sean Grimmond
     Phosphoregulators: Protein Kinases and Protein Phosphatases of Mouse
     Genome Res. 2003 13: 1443-1454. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1443

Harukata Miki, Mitsutoshi Setou, RIKEN GER Group, GSL Members, and Nobutaka Hirokawa
     Kinesin Superfamily Proteins (KIFs) in the Mouse Transcriptome
     Genome Res. 2003 13: 1455-1465. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1455

Yuka Kawasawa, Louise M. McKenzie, David P. Hill, Hidemasa Bono, RIKEN GER Group, GSL Members, and Masashi Yanagisawa
     G Protein-Coupled Receptor Genes in the FANTOM2 Database
     Genome Res. 2003 13: 1466-1477. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1466

Masaaki Furuno, Takeya Kasukawa, Rintaro Saito, Jun Adachi, Harukazu Suzuki, Richard Baldarelli, Yoshihide
Hayashizaki, and Yasushi Okazaki
     CDS Annotation in Full-Length cDNA Sequence
     Genome Res. 2003 13: 1478-1487. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1478

METHODS:

    Jun Kawai and Yoshihide Hayashizaki
     DNA Book
     Genome Res. 2003 13: 1488-1495. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1488

Lynn M. Schriml, David P. Hill, Judith A. Blake, Hidemasa Bono, Anthony Wynshaw-Boris, William J. Pavan, Brian Z. Ring, Kirk Beisel, Mitsutoshi Setou, RIKEN GER Group, GSL Members, and Yasushi Okazaki
     Human Disease Genes and Their Cloned Mouse Orthologs: Exploration of the FANTOM2 cDNA
     Sequence Data Set
     Genome Res. 2003 13: 1496-1500. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1496

RESOURCES:

Boris Lenhard, Claes Wahlestedt, and Wyeth W. Wasserman
     GeneLynx Mouse: Integrated Portal to the Mouse Genome
     Genome Res. 2003 13: 1501-1504. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1501

Richard M. Baldarelli, David P. Hill, Judith A. Blake, Jun Adachi, Masaaki Furuno, Dirck Bradt, Lori E. Corbani, Sharon Cousins, Kenneth S. Frazer, Dong Qi, Longlong Yang, Sridhar Ramachandran, Deborah Reed, Yunxia Zhu, Takeya Kasukawa, Martin Ringwald, Benjamin L. King, Lois J. Maltais, Louise M. McKenzie, Lynn M. Schriml, Donna Maglott, Deanna M. Church, Kim Pruitt, Janan T. Eppig, Joel E. Richardson, Jim A. Kadin, and Carol J. Bult
     Connecting Sequence and Biology in the Laboratory Mouse
     Genome Res. 2003 13: 1505-1519. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1505

Takeshi Nagashima, Diego G. Silva, Nikolai Petrovsky, Luis A. Socha, Harukazu Suzuki, Rintaro Saito, Takeya
Kasukawa, Igor V. Kurochkin, Akihiko Konagaya, and Christian Schönbach
     Inferring Higher Functional Information for RIKEN Mouse Full-Length cDNA Clones With FACTS
     Genome Res. 2003 13: 1520-1533. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1520

Harukazu Suzuki, Rintaro Saito, Mutsumi Kanamori, Chikatoshi Kai, Christian Schönbach, Takeshi Nagashima, Junko Hosaka, and Yoshihide Hayashizaki
     The Mammalian Protein–Protein Interaction Database and Its Viewing System That Is Linked to the
     Main FANTOM2 Viewer
     Genome Res. 2003 13: 1534-1541. [Abstract] [Full Text]
     http://www.genome.org/cgi/content/abstract/13/6b/1534

Takeya Kasukawa, Masaaki Furuno, Itoshi Nikaido, Hidemasa Bono, David A. Hume, Carol Bult, David P. Hill,
Richard Baldarelli, Julian Gough, Alexander Kanapin, Hideo Matsuda, Lynn M. Schriml, Yoshihide Hayashizaki, Yasushi Okazaki, and John Quackenbush
     Development and Evaluation of an Automated Annotation Pipeline and cDNA Annotation System
     Genome Res. 2003 13: 1542-1551. [Abstract] [Full Text] [Supplemental Research Data]
     http://www.genome.org/cgi/content/abstract/13/6b/1542

ABSTRACTS:

Serge Batalov and Colin F. Fletcher
     Exon Structure Analysis, Ortholog Identification, and SNP Candidate Screening by Mapping Mouse
     RIKEN Sequences to Multiple Genome Assemblies
     Genome Res. 2003 13: 1552-1553. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1552

Hidenori Kiyosawa, Tsugumi Kawashima, Yuki Hasegawa, Itaru Yamanaka, Katsunaga Sakai, Shinji Kondo, RIKEN GER Group, GSL Members, and Yoshihide Hayashizaki
     Introduction of RIKEN-GenoMapper, Mapping Viewer System
     Genome Res. 2003 13: 1554-1555. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1554

Serge Batalov, Andrew I. Su, Keith A. Ching, and Colin F. Fletcher
     Functional Annotation of RIKEN Mouse cDNA Clones Using GNF Expression Atlas
     Genome Res. 2003 13: 1556-1557. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1556

Yoichi Takenaka and Hideo Matsuda
     Analysis of Gene Expression Profiles Based on Clustering
     Genome Res. 2003 13: 1558. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1558

Diego G. Silva, Christian Schönbach, Vladimir Brusic, Luis A. Socha, Takeshi Nagashima, RIKEN GER Group, GSL Members, and Nikolai Petrovsky
     Identification of Novel "Pathologs" (Human Disease-Related Gene Candidates) From the RIKEN
     Full-Length Mouse cDNA Data Set
     Genome Res. 2003 13: 1559. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1559

Igor V. Kurochkin, RIKEN GER Group, GSL Members, Akihiko Konagaya, Takeshi Nagashima, and Christian
Schönbach
     Identification of Potential Peroxisomal Proteins in Mouse
     Genome Res. 2003 13: 1560. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1560

Yuko Watanabe, Seiji Nishiguchi, Makoto Watanabe, Kazunori Shimada, RIKEN GER Group, GSL Members, Koji Koyama, and Hiromichi Yamanishi
     The Mouse Neuronal Protein 15.6 Gene Family
     Genome Res. 2003 13: 1561. [Full Text]
     http://www.genome.org/cgi/content/full/13/6b/1561

COVER CAPTION:

Cover The illustration symbolizes the "RIKEN Mouse Genome Encyclopedia" project: the whole system
             from mouse house to database. The left photo is the BK6 mouse used for sequencing in this project. The
             yellow cup below it represents the RISA system (RIKEN Integrated Sequence Analyzer). Data output is
             delivered and stored in a PC, and clones are stored as printed material as in the "DNA Book" in this        issue. The right photo is the FANTOM2 collaborative members at the Cherry Blossom Meeting held by        RIKEN GSC in 2002. (Cover designed by Dr. Chie Owa; For details, see Kawai et al., pp. 1488-1495.)
             http://www.genome.org/cgi/content/short/13/6b/1488



Additional References:

1. Saha S, Ansari AZ, Jarell KA, and Ptashne M, "RNA Sequences that Work as Transcriptional Activating Regions".

2. Lee JM, and Sonnhammer ELL, "Genomic Gene Clustering Analysis of Pathways in Eukaryotes".

3. Blumenthal T, Evans D, Link CD, Guffanti A, Lawson D, Thierry-Mieg J, Thierry-Mieg D, Chiu WL, Duke K, Kiraly M, and Kim SK, "A Global Analysis of Caenorhabditis elegans Operons".

4. Storz G, "An Expanding Universe of Noncoding RNAs".

5. Eddy SR, "Non-Coding RNA Genes and the Modern RNA World".

6. Huttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie J-P, and Brosius J, "RNomics: An Experimental Approach that Identifies 201 Candidates for Novel, Small, Non-Messenger RNAs in Mouse".

7. Hovsepian JA, and Frenster JH, "RNA-Induced Melting of DNA during Selective Gene Transcription".

8. Frenster JH, "Ultrastructural Probes of Active DNA Sites, and the RNA Activators of DNA".

9. Special Issue of Genome Research, vol. 13, no. 6b, pp. 1265-1561 (June 2, 2003).
Report of "RIKEN Mouse Genome Encyclopedia" project: the whole system from mouse house to database.
 



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