American Association for Cancer Research, 91st Annual Meeting, April 1-5, 2000, The Moscone Center, San Francisco, California, U.S.A.

Schedule of Events

Saturday, April 1, 2000

Public Forum and Ask-the-Expert Sessions 10:00 - 5:00 p.m.
Associate Member Grant Writing Workshop 12:00 - 6:00 p.m.
Educational Sessions 12:00 - 2:00 p.m.
Methods Workshops 2:00 - 6:00 p.m.
Educational Sessions 2:15 - 4:15 p.m.
Educational Sessions 4:30 - 6:30 p.m.
Women in Cancer Research Charlotte Friend Memorial Lecture and Reception "Of Microbes, Mice, and (Wo)men: Grappling with the Wrath of Alkylating Agents" Leona D. Samson 6:30 - 8:30 p.m.

Associate Member Reception 7:30 - 8:30 p.m.

Opening Reception 8:30 - 11:00 p.m.

Sunday, April 2, 2000

Meet-the-Expert Sunrise Sessions 7:00 - 8:00 a.m.

Tobacco and Cancer, Stephen S. Hecht
p13 Kinase, Julian Downward
Ink 4/ARF Tumor Suppressor Locus, Martine F. Roussel
Perspectives on Cancer Chemotherapy: Past, Present, and Future, Emil Frei, III
Cloning Animals, Tony Perry and Teru Wakayama
Quality of Life Issues, TBA
The Steroid Receptor Superfamily, TBA
Hepatitis Virus and Liver Cancer, Setsuo Hirohashi
Signaling by IFGs, David R. Clemmons
Inherited Carcinomas of the Kidney, Berton Zbar
New Methods in Clinical Trials, Susan G. Arbuck
Cell Cycle/Checkpoints, TBA

NIH Grants Forum 7:00 - 8:00 a.m.

Presidential Address,
"Pancreatic Cancer: New Targets, New Treatments" Daniel D. Von Hoff 8:00 - 9:00 a.m.

Poster Sessions 8:00 - 11:00 a.m.

Presentation of Awards 9:00 - 9:15 a.m.

Plenary Session 9:15 - 11:30 a.m.
"Genetic Approaches to Cancer Prevention" Malcolm C. Pike
"Genomics: What is it, Where is it Going?" Francis Collins
"Chromatin" Adrian P. Bird
"25 Years of Monoclonal Antibodies: Are We There Yet?" Ellen S. Vitetta
"Therapeutic Targeting of Genetic Alterations" Dennis J. Slamon

AACR-Pezcoller International Cancer Research Award Lecture, Awardee TBA 11:30 - 12:30 p.m.

Poster Sessions 11:30 - 2:30 p.m.
Poster Discussion Sessions 1:30 - 4:30 p.m.
Minisymposia 1:30 - 5:00 p.m.
Symposia 2:15 - 4:45 p.m.

Transcription, Beverly M. Emerson (Chairperson), Laura D. Attardi, Rudy Grosschedl, Joseph R. Nevins, Daniel A. Haber

Radiation Oncology and Chemotherapy: Understanding the Issues, Silvia Formenti and C. Norman Coleman (Chairpersons), Rebecca S. Gelman, Beverly A. Teicher, Barbara A. Conley

Molecular Alterations in Bladder Cancer: Translation from Bench to Bedside, Margaret Knowles and Richard J. Cote (Chairpersons), Peter A. Jones, Frederic M. Waldman, Carlos Cordon-Cardo

Diet, Nutrition, and Cancer: Examining the Link, John P. Pierce (Chairperson), Cheryl L. Rock, David J. Hunter, Zora Djuric, Elena Martinez, Johanna W. Lampe

Molecular-targeted Therapeutics: New Strategies, William G. Kaelin, Jr. (Chairperson), Frank McCormick, Steven F. Dowdy, Roland Burli, Stephen H. Friend

AACR-Joseph H. Burchenal Clinical Research Award Lecture, Waun Ki Hong 5:30 - 6:30 p.m. Careers Symposium Sponsored by Minority Issues Committee 6:30 - 8:30 p.m.

Annual Reception 9:00 - 11:30 p.m.

Monday, April 3, 2000

Women in Cancer Research Leila Diamond Mentoring Breakfast 6:30 - 8:00 a.m.

Meet-the-Expert Sunrise Sessions 7:00 - 8:00 a.m.

The E-Cadherin System: Function and Dysfunction in Cancer, Barry Gumbiner
Growth Regulation Through Protein Phosphorylation, Tony Hunter
Ubiquitin/Proteasome System, Michele Pagano Drug Discovery, Neil W. Gibson
Genetic Imprinting, Benjamin Tycko
Physical Activity and Cancer, Leslie Bernstein
COX-2 Regulation and Function, Harvey Herschman
Helicobacter pylori and Gastric Cancer, Eiichi Tahara
The Li-Fraumeni Syndrome and Cancer, Louise C. Strong
Overview of Cancer in High Risk Families, Frederick P. Li
Molecular Approaches to Cancer Detection, Jonathan W. Uhr
Hypoxia and Cancer, Amato J. Giaccia

Symposia 8:00 - 10:30 a.m.

Chemoprevention of Cancer of the Respiratory Tract, Lee W. Wattenberg (Chairperson), Steven A.Belinsky, Andrew J. Dannenberg, Jonathan M. Kurie, Stephen S. Hecht

Mitogen-activated Protein Kinase Signaling Cascades and Oncogenesis, Channing J. Der (Chairperson), Michael J. Weber, Roger J. Davis, Alan R. Saltiel

Melanoma, Nick Hayward (Chairperson), Jeffrey M. Trent, Lynda Chin

Apoptosis: Basic Mechanisms, John C. Reed (Chairperson)

Angiogenesis, Douglas Hanahan and S. Gail Eckhardt (Chairpersons), Erkki Ruoslahti, Israel Vlodovsky, David P. Carbone

Poster Sessions 8:00 - 11:00 a.m.

Minisymposia 8:30 - 12:00 noon

Poster Discussion Sessions 8:30 - 11:30 a.m.

Poster Sessions 11:30 - 2:30 p.m.

AACR-Cornelius P. Rhoads Memorial Award Lecture, Nikola P. Pavletich 12:00 - 1:00 p.m.

Poster Discussion Sessions 12:00 - 3:00 p.m.

Minisymposia 1:30 - 5:00 p.m.

Symposia 2:30 - 5:00 p.m.

The Cancer-Chromatin Connection, Alan P. Wolffe (Chairperson), Henk Stunnenberg, Trevor K. Archer, Douglas Dean

Apoptosis: Therapeutic Implications, John A. Hickman (Chairperson), David H. Lynch, Robert Lutz, Caroline Dive, Philip E. Branton

Advances and Challenges in Brain Cancer Research, Francis Ali-Osman and Webster K. Cavenee (Chairpersons), Mark D. Noble, Ole D. Laerum, Darell D. Bigner, Paul Kleihues

Cancer Vaccines, Drew M. Pardoll (Chairperson)

DNA Repair and Genetic Stability, James E. Cleaver (Chairperson), Thea D. Tlsty, Keith W. Caldecott, Maria Jasin, Steven I. Reed

Poster Sessions 3:00 - 6:00 p.m.

Poster Discussion Sessions 3:30 - 6:30 p.m.

AACR-Bruce F. Cain Memorial Award Lecture, Axel Ullrich 5:30 - 6:30 p.m.

Women in Cancer Research Business Meeting 6:30 - 8:30 p.m.

Tuesday, April 4, 2000

Associate Member Council Sunrise Session: Communication in Silence 6:30 - 8:00 a.m.

Meet-the-Expert Sunrise Sessions 7:00 - 8:00 a.m.

Clinical Trials in Gene Therapy, Stanton L. Gerson
TGF-Beta Receptor Signaling, Jeffrey L. Wrana
Monoclonal Antibodies in the Treatment of Hematologic Malignancies, TBA
New Platinum Compounds, Nick Farrell
Mammary Stem Cells and Carcinogenesis in Mice, Daniel D. Medina and Gilbert Smith
Inhibition of Bone Resorption, James R. Berenson
Cancer Treatment-related Secondary Tumors, Margaret A. Tucker
Viruses and the Immune System as Promoters of Cancer Development, Jay A. Levy
HIV-related Malignancies, Ellen G. Feigal
Pancreatic Cancer, James L. Abbruzzese
Molecular Fingerprinting and Its Impact on Therapy, Edison Tak-Bun Liu
Radiation Oncology in Evolution: From Empirical to Targeted Therapy, W. Gillies McKenna

Symposia 8:00 - 10:30 a.m.

Mouse Models and Cancer, Terry A. Van Dyke (Chairperson), Douglas Hanahan, Guillermina Lozano, Ronald A. DePinho

Cellular Microenvironments and Cancer Biology: Processes That Influence Normal Function and Metastasis, Mina J. Bissell and Ann F. Chambers (Chairpersons), Mary J. C. Hendrix, Robert Radinsky

The Genetic Epidemiology of Prostate Cancer, Alice S. Whittemore and Otis W. Brawley (Chairpersons), Edward Giovannucci, William B. Isaacs, Brian E. Henderson, Atsuko Shibata

Exploiting the Genetic Defects of Pediatric Tumors, Mark A. Israel (Chairperson), Lee J. Helman, Perry D. Nisen, Donald M. O'Rourke, Luke J. Whitesell

Minorities and Career Symposium, TBA

Poster Sessions 8:00 -11:00 a.m.

Minisymposia 8:30 - 12:00 noon

Poster Discussion Sessions 8:30 - 11:30 a.m.

Late-Breaking Research Session 10:45 - 12:00 noon

Poster Sessions 11:30 - 2:30 p.m.

AACR-Richard and Hinda Rosenthal Foundation Award Lecture, Edison Tak-Bun Liu 12:00 - 1:00 p.m.

Poster Discussion Sessions 12:00 - 3:00 p.m.

Special Lecture: National Cancer Institute Director, Richard D. Klausner 1:00 - 2:00 p.m.

Minisymposia 1:30 - 5:00 p.m.

NCI Board of Scientific Advisors "NCI Listens" Session 2:15 - 3:15 p.m.

Symposia 3:00 - 5:30 p.m.

Epigenetics of Cancer: New Mechanisms for Silencing Tumor Suppressor Genes, Paula M. Vertino (Chairperson), Stephen B. Baylin, En Li, Joseph F. Costello

Cytotoxic Chemotherapy: Making the Transition to the New Millennium, Susan P. C. Cole and Joseph R. Bertino (Chairpersons), Anne H. Dantzig, Kathleen W. Scotto, Paul S. Meltzer

Her-2 neu as a Therapeutic Target in Breast Cancer: Molecular Biology to the Clinic, Edith A. Perez and Karen S. H. Antman (Chairpersons), Yosse Yarden

Molecules, Genes, and Pathways to Cancer: New Methods and Approaches in Epidemiology, John D. Potter (Chairperson), Rashmi Sinha, Robert Haile, Muin J. Khoury, Harvey W. Mohrenweiser

New Horizons in the Treatment of Intraepithelial Neoplasia, Joyce A. O'Shaughnessy and TBA (Chairpersons)

Poster Sessions 3:00 - 6:00 p.m.

Poster Discussion Sessions 3:30 - 6:30 p.m.

AACR-G.H.A. Clowes Memorial Award Lecture, Elizabeth H. Blackburn 5:30 - 6:30 p.m.

Wednesday, April 5, 2000

Meet-the-Expert Sunrise Sessions 7:00 - 8:00 a.m.

Nuclear Organization and Gene Expression, David L. Spector
Her-2 neu Signaling and Epithelial Neoplasms, Yosse Yarden
p53: Structure, Function, and Clinical Potential, Karen H. Vousden
Pharmacogenomics: Drug Discovery in the Post Genomic Era, Roland Somogyi
Tumor-Stromal Interactions, Gerald R. Cunha
Genetic Testing, TBA
Tamoxifen and SERMS, C. Kent Osborne
Papillomaviruses and Cervical Cancer, Denise A. Galloway
Mismatch Repair and Cancer Therapy, Robert Brown
Lung Cancer, Takashi Takahashi
New Approaches in Cancer Cytogenetics, Joe W. Gray
Imaging, Angiogenesis, and Vascular Function, Rakesh K. Jain

Poster Sessions 8:00 - 11:00 a.m.

Poster Discussion Sessions 8:30 - 11:30 a.m.

AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention Lecture, Walter C. Willett 8:00 - 9:00 a.m.

Minisymposia 8:15 - 11:45 a.m.

AACR-DeWitt S. Goodman Lecture, John D. Potter 9:00 - 9:45 a.m.

Special Late-Breaking Symposium: In the Forefront of Advances in Cancer Research, TBA 9:00 - 11:30 a.m.

Poster Sessions 11:30 -2:30 p.m.

Poster Discussion Sessions 12:00 - 3:00 p.m.

Minisymposia 12:15 - 3:45 p.m.

Symposia 12:30 - 3:00 p.m.

Aging and Cancer: Focusing on Preneoplastic Changes, Jean-Pierre Issa (Chairperson), Leonard Guarente, Olivia M. Pereira-Smith, Ronald A. DePinho

Colorectal Cancer, Stanley R. Hamilton (Chairperson)

Development and Cancer, Matthew P. Scott (Chairperson)

American Association for Cancer Research
Public Ledger Building, Suite 826
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http://www.aacr.org/