Frenster JH, "Ultrastructural
Probes of Active DNA Sites, and the RNA Activators of DNA"., (PowerPoint
Presentation).
A brief history of Activator RNAs:
Links to Euchromatin and Activator RNA Reviews:
Links to Euchromatin and Activator RNA Research:
Links to Ultrastructural
Probes of DNase I-Sensitive Sites:
Links to
RNA as a Therapeutic Agent:
Links to Hodgkin Lymphoma Immuno-Pathology:
Links to Activated T-Lymphocyte Immunotherapy:
Links to Medical
Systems Biology:
Links to Selective
Gene Transcription:
Links to RNA-Induced
Epigenetics:
Links to RNA-Induced
Embryogenesis:
Links to RNA and
Biological Causality:
Links to Reprogramming
and Neoplasia:
Euchromatin and Activator RNA Reviews :
26. Place RF, Li L-C, Pookot D, Noonan EJ, and Dahiya R, "MicroRNA-373 induces expression of genes with complementary promoter sequences".
25. Zhu X, Ling J, Zhang L, Pi W, Wu M, and Tuan D, "A facilitated tracking and transcription mechanism of long-range enhancer function".
24. Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham
AT, Stadler PE, Hertel J, Hackermüller J, Hofacker IL, Bell
I, Cheung E, Drenkow J, Dumais E, Patel S, Helt G, Ganesh M, Ghosh S,
Piccolboni A, Sementchenko V, Tammana H, and Gingeras TR,
"RNA Maps Reveal
New RNA Classes and a Possible Function for Pervasive Transcription".
23. Rossi JJ, "Transcriptional activation by small RNA duplexes".
22. Li L-C, Okino ST, Zhao H, Pookot D, Place RF, Urakami S, Enokida
H, and Dahiya R,
"Small dsRNAs induce
transcriptional activation in human cells".
21. Pennacchio LA, Ahituv N, Moses AM, Prabhakar S, Nobrega MA, Shoukry M, Minovitsky S, Dubchak I, Holt A, Lewis KD, Plajzer-Frick I, Akiyama J, De Val S, Afzal V, Black BL, Couronne O, Eisen MB, Visel A, and Rubin EM, "In vivo enhancer analysis of human conserved non-coding sequences".
20. Goodrich JA, and Kugel JF, "Non-coding-RNA regulators of RNA polymerase II transcription".
19. Eder M, and Scherr M, "MicroRNA and Lung Cancer".
18. Hovsepian JA, and Frenster JH, "Reprogramming as an Approach to Neoplasms".
17. Frenster JH, and Hovsepian JA, "Activator RNA Exchange during Interphase Chromatin Reprogramming".
16. Hovsepian JA, and Frenster JH, "Bioassays of Isolated Nuclear RNA Species as Activators of DNA Transcription".
15. Hovsepian JA, and Frenster JH, "Euchromatin as an Extensile Force within Mammalian Cell Nuclei".
14. Knight J, "Gene regulation: Switched on to RNA".
13. Gottesfeld JM, and Barbas CF III, "RNA as a Transcriptional Activator".
12. Numata K, Kanai A, Saito R, Kondo S, Adachi J, Wilming LG, Hume DA, RIKEN GER Group, GSL Members, Hayashizaki Y, and Tomita M, "Identification of Putative Noncoding RNAs Among the RIKEN Mouse Full-Length cDNA Collection".
11. Lai E, "RNA Sensors and Riboswitches: Self-Regulating Messages".
10. Hovsepian JA, and Frenster JH, "RNA-Induced Melting of DNA during Selective Gene Transcription".
9. Storz G, "An Expanding Universe of Noncoding RNAs".
8. Eddy SR, "Non-Coding RNA Genes and the Modern RNA World".
7. Frenster JH, "Activation of DNA Transcription within Repressed Chromatin".
6. Frenster JH, "Selective Gene De-Repression by De-Repressor RNA".
5. Frenster JH, "Selective Control of DNA Helix Openings during Gene Regulation".
4. Frenster JH, Nakatsu SL, and Masek MA, "Ultrastructural Probes of DNA Templates within Human Bone Marrow and Lymph Node Cells".
3. Frenster JH, and Herstein PR, "Gene De-Repression".
2. Frenster JH, "Mechanisms of Repression and De-Repression within Interphase Chromatin".
1. DeCarvalho S, "Effect
of RNA from Normal Human Marrow on Leukaemic Marrow In-Vivo".
Euchromatin and Activator RNA Research:
43. Frenster JH, and Hovsepian JA, “Models of Embryonic Gene-Induced Initiation and Reversion of Adult Neoplasms”.
42. Frenster JH, and Hovsepian JA, "DNase-I Ultrastructural Probe Sites and Kissing Chromosomes".
41. Frenster JH, and Hovsepian JA,
"DNA-DNA Tetraplex
Model of Paired Sense-Antisense RNA Synthesis".
40. Li L-C, Okino ST, Zhao H, Pookot D, Place RF, Urakami S, Enokida
H, and Dahiya R,
"Small dsRNAs induce
transcriptional activation in human cells".
39. Lee YS, and Dutta A, "The tumor suppressor microRNA let-7 represses the HMGA2 oncogene".
38. Mayr C, Hemann MT, and Bartel DP,
"Disrupting the
Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation".
37. Hayes GD, and Ruvkun G, "Misexpression of the Caenorhabditis elegans miRNA let-7 is Sufficient to Drive Developmental Programs".
36. Lanctôt C, Cheutin T, Cremer M, Cavalli G, and Cremer T, "Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions".
35. Hovsepian JA, and Frenster JH,
"Chromosome-Chromosome
Contact Points and Paired Sense-Antisense RNA Synthesis".
34. Frenster JH, and Hovsepian JA, "Activator RNA Initiation of the DNA Transcription Bubble".
33. Green SJ, Lubrich D, and Turberfield AJ, "DNA hairpins: fuel for autonomous DNA devices".
32. Frenster JH, and Hovsepian JA, "Kissing Chromosomes and Paired
Sense-Antisense RNA Synthesis".
71st Cold Spring Harbor Symposium on Quantitative Biology", Program
page 62, May 31-June 5, 2006.
31. Kioussis D, "Gene Regulation: Kissing Chromosomes", Nature vol. 435, no. 7042, pp. 579-580 (June 2, 2005). http://www.nature.com/nature/journal/v435/n7042/full/435579a.html
30. Frenster JH, and Hovsepian JA, "Ultrastructure of Euchromatin Contact Points between the Closed Loops of Adjacent Interphase Chromosomes".
29. Shin JT, Priest JR, Ovcharenko I, Ronco A, Moore RK, C. Burns
CG, and MacRae CA,
"Human-zebrafish
non-coding conserved elements act in vivo to regulate transcription".
28. Song X, Sun Y, and Garen A, "Roles of PSF protein and VL30 RNA in reversible gene regulation".
27. Kuwabara T, Hsieh J, Nakashima K, Warashina M, Taira K, and Gage FH, "The NRSE smRNA specifies the fate of adult hippocampal neural stem cells".
26. Ling J, Baibakov B, Pi W, Emerson BM, and Tuan D, "The HS2 Enhancer of the b-globin Locus Control Region Initiates Synthesis of Non-coding, Polyadenylated RNAs Independent of a cis-linked Globin Promoter".
25. Hovsepian JA, and Frenster JH, "Sense and Antisense during RNA Initiation of the DNA Transcription Bubble".
24. Frenster JH, and Hovsepian JA, "Ultrastructure of Closed Loops within Euchromatin of Isolated Lymphocyte Nuclei".
23. Kuwabara T, Hsieh J, Nakashima K, Taira K, and Gage FH, "A Small Modulatory dsRNA Specifies the Fate of Adult Neural Stem Cells".
22. Coleman KM, Lam V, Jaber BM, Lanz RB, Smith CL, "SRA coactivation of estrogen receptor-alpha is phosphorylation-independent, and enhances 4-hydroxytamoxifen agonist activity".
21. Frenster JH, and Hovsepian JA, "Activator RNA Exchange during Interphase Chromatin Reprogramming".
20. Seitz H, Youngson N, Lin S-P, Dalbert S, Paulsen M, Bachellerie J-P, Ferguson-Smith AC, and Cavaille J, "Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene".
19. Sleutels F, Zwart R, and Barlow DP, "The non-coding Air RNA is required for silencing autosomal imprinted genes".
18. Persengiev SP, Zhu X, and Green MR, "Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)".
17. Coughlin CM, Vance BA, Grupp SA, and Vonderheide RH, "RNA-transfected CD40-activated B cells induce functional T cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy".
16. Iwakiri D, Eizuru Y, Tokunaga M, and Takada K, "Autocrine Growth of Epstein-Barr Virus-Positive Gastric Carcinoma Cells Mediated by an Epstein-Barr Virus-Encoded Small RNA".
15. Santulli-Marotto S, Nair SK, Rusconi C, Sullenger B, and Gilboa E, "Multivalent RNA Aptamers That Inhibit CTLA-4 and Enhance Tumor Immunity".
14. Ji P, Diederichs S, Wang W, Böing S, Metzger R, Schneider PM, Tidow N, Brandt B, Buerger H, Bulk E, Thomas M, Berdel1 WE, Serve H and Müller-Tidow C, "MALAT-1, a novel noncoding RNA, and thymosin b4 predict metastasis and survival in early-stage non-small cell lung cancer".
13. Ling J, Pi W, Yu X, Bengra C, Long Q, Jin H, Seyfang A, and Tuan D, "The ERV-9 LTR Enhancer is Not Blocked by the HS5 Insulator and Synthesizes Through the HS5 Site Non-Coding, Long RNAs that Regulate LTR Enhancer Function", Nucleic Acids Research, vol. 31, no. 15, pp. 4582-4596 (August 1, 2003).
12. Lanz RB, Chua SS, Barron N, Söder BM, DeMayo F, and O'Malley BW, "Steroid Receptor RNA Activator Stimulates Proliferation as Well as Apoptosis In Vivo".
11. Frenster JH, and Hovsepian JA, "Overshoot in Late Telophase for RNA Re-Programming of Mitotic Chromatin".
10. Buskirk AR, Kehayova PD, Landrigan A, and Liu DR, "In Vivo Evolution of an RNA-Based Transcriptional Activator".
9. Sudarsan N, Barrick JE, and Breaker RR, "Metabolite-Binding RNA Domains are Present in the Genes of Eukaryotes".
8. Saha S, Ansari AZ, Jarell KA, and Ptashne M, "RNA Sequences that Work as Transcriptional Activating Regions".
7. Lanz RB, Razani B, Goldberg AD, and O'Malley BW, "Distinct RNA Motifs are Important for Coactivation of Steroid Hormone Receptors by Steroid Receptor RNA Activator (SRA)".
6. Kwek KY , Murphy S , Furger A , Thomas B , O'Gorman W , Kimura H , Proudfoot NJ and Akoulitchev A, "U1 snRNA Associates with TFIIH and Regulates Transcriptional Initiation".
5. Frenster JH, and Hovsepian JA, "RNA Feedback Mechanisms during Eukaryotic Gene Regulation".
4. Frenster JH, "Yeast RNA Re-Programming of Already-Active Mammalian Chromatin".
3. Frenster JH, "Uni-Polar Clustering of Lymphocyte DNA Templates Toward Neoplastic Target Cells Within Hodgkin's Disease Lymph Nodes".
2. Frenster JH, "Oncogenes as Molecular Targets within Active Chromatin".
1. Frenster JH, "Nuclear RNA Species Activate
DNA Transcription within Chromatin".
For Further Information or Feedback:
e-mail: frenster@euchromatin.net
Phone: +1 650 367 6483
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